


DEEPMATCHER
DEEPMATCHER
®
®
DEEPMATCHER® is Syntekabio’s proprietary AI-driven drug candidate discovery platform.
By integrating advanced AI algorithms with high-performance supercomputing infrastructure,
we analyze vast chemical libraries with unprecedented speed and precision, overcoming
the physical limitations of traditional drug discovery.
DEEPMATCHER® is Syntekabio’s proprietary AI-driven drug candidate discovery platform.
By integrating advanced AI algorithms with high-performance supercomputing infrastructure, we analyze vast chemical libraries with unprecedented speed and precision, overcoming the physical limitations of traditional drug discovery.
A Paradigm Shift in Drug Discovery
DEEPMATCHER® resolves the chronic issues of repetitive trial-and-error and bottlenecks in traditional drug development. DEEPMATCHER® predicts structural limitations at the earliest stages of research and provides optimized development paths, maximizing R&D efficiency and significantly increasing the probability of success.
This marks the beginning of a transformative shift in the entire drug discovery research flow.
Making AI Drug Discovery Practical:
The Role of DEEPMATCHER®
Making AI Drug Discovery Practical:
The Role of DEEPMATCHER®


Realizing AI: The Synergy of
Algorithms and Infrastructure
Our AI drug discovery technology is built on sophisticated algorithms and extensive simulation experience.
Backed by extensive computational and in silico simulation experience across a wide range of proteins,
our technology is designed to translate directly into tangible research outcomes. Utilizing our massive parallel processing supercomputing center (ABSC), we perfectly simulate complex interactions between proteins and compounds in an in silico environment.
Beyond mere theory, our platform delivers actionable results through precision algorithms that
lead to actual research milestones.




AI-Powered Matching —
Enhancing Precision in Drug Discovery
DEEPMATCHER® apply state-of-the-art AI models that interpret protein-drug binding as a form of 'language' to analyze molecular interactions with superior accuracy.

Unrivaled Efficiency
Supercomputing-based massive parallel processing dramatically shortens drug discovery timelines and significantly reduces R&D costs.

Unrivaled Efficiency
Supercomputing-based massive parallel processing dramatically shortens drug discovery timelines and significantly reduces R&D costs.

Tackling Challenging Targets
We enable the discovery of drug candidates even for intractable diseases and novel targets.

Tackling Challenging Targets
We enable the discovery of drug candidates even for intractable diseases and novel targets.

Precise Predictive Accuracy
DEEPMATCHER® harnesses language model technology to precisely analyze molecular interactions, maximizing your probability of success.

Precise Predictive Accuracy
DEEPMATCHER® harnesses language model technology to precisely analyze molecular interactions, maximizing your probability of success.
End-to-End Support
From initial discovery to optimization and efficacy validation, we provide a comprehensive one-stop solution.
End-to-End Support
From initial discovery to optimization and efficacy validation, we provide a comprehensive one-stop solution.

Unrivaled Efficiency
Supercomputing-based massive parallel processing dramatically shortens drug discovery timelines and significantly reduces R&D costs.

Precise Predictive Accuracy
DEEPMATCHER® harnesses language model technology to precisely analyze molecular interactions, maximizing your probability of success.

Tackling Challenging Targets
We enable the discovery of drug candidates even for intractable diseases and novel targets.
End-to-End Support
From initial discovery to optimization and efficacy validation, we provide a comprehensive one-stop solution.
Key Processes of DEEPMATCHER®
Key Processes of DEEPMATCHER®



01
Target Protein Input
Structural information of the target protein is converted into optimized data compatible with AI language models.
01
Target Protein Input
Structural information of the target protein is converted into optimized data compatible with AI language models.
01
Target Protein Input
Structural information of the target protein is converted into optimized data compatible with AI language models.
02
Hyper-fast AI Screening
We conduct ultra-high-speed virtual screening of over 10 billion compound databases using LM-VS™ technology to select effective candidates.
02
Hyper-fast AI Screening
We conduct ultra-high-speed virtual screening of over 10 billion compound databases using LM-VS™ technology to select effective candidates.
02
Hyper-fast AI Screening
We conduct ultra-high-speed virtual screening of over 10 billion compound databases using LM-VS™ technology to select effective candidates.
03
Precision Prediction & Fine-Tuning
MD simulations are performed on selected candidates to evaluate binding energy and position, deriving the top 100 candidates.
03
Precision Prediction & Fine-Tuning
MD simulations are performed on selected candidates to evaluate binding energy and position, deriving the top 100 candidates.
03
Precision Prediction & Fine-Tuning
MD simulations are performed on selected candidates to evaluate binding energy and position, deriving the top 100 candidates.
04
AI-based Validation
We proactively eliminate candidates with high clinical failure risks and verify safety through ADMET profile predictions.
04
AI-based Validation
We proactively eliminate candidates with high clinical failure risks and verify safety through ADMET profile predictions.
04
AI-based Validation
We proactively eliminate candidates with high clinical failure risks and verify safety through ADMET profile predictions.
05
Final Candidate Delivery
We provide essential data packages for the final candidates to support seamless transitions to subsequent development stages.
05
Final Candidate Delivery
We provide essential data packages for the final candidates to support seamless transitions to subsequent development stages.
05
Final Candidate Delivery
We provide essential data packages for the final candidates to support seamless transitions to subsequent development stages.
A New Standard in Docking
— Proven Performance of DEEPMATCHER®
01
Expansive Search Range
Our flexible mold-based docking technology accounts for
protein flexibility, expanding the search space and ensuring chemical diversity.
01
Expansive Search Range
Our flexible mold-based docking technology accounts for
protein flexibility, expanding the search space and ensuring chemical diversity.
01
Expansive Search Range
Our flexible mold-based docking technology accounts for
protein flexibility, expanding the search space and ensuring chemical diversity.
02
Superior Accuracy
DEEPMATCHER® improves accuracy by 15–30% compared
to conventional algorithms, ensuring a higher probability of clinical success.
02
Superior Accuracy
DEEPMATCHER® improves accuracy by 15–30% compared
to conventional algorithms, ensuring a higher probability of clinical success.
02
Superior Accuracy
DEEPMATCHER® improves accuracy by 15–30% compared
to conventional algorithms, ensuring a higher probability of clinical success.
03
Optimal Cost-Effectiveness
By supporting the entire process from discovery to validation, we radically reduce the time and capital required for drug development.
03
Optimal Cost-Effectiveness
By supporting the entire process from discovery to validation, we radically reduce the time and capital required for drug development.
03
Optimal Cost-Effectiveness
By supporting the entire process from discovery to validation, we radically reduce the time and capital required for drug development.


DEEPMATCHER®
DEEPMATCHER®
Key Applications
Key Applications
Drug Repurposing
Identifying new indications for FDA-approved drugs and existing candidate substances.
Drug Repurposing
Identifying new indications for FDA-approved drugs and existing candidate substances.
Drug Repurposing
Identifying new indications for FDA-approved drugs and existing candidate substances.
Novel Modality Development
Providing advanced technology for modalities requiring sophisticated deep learning, such as Molecular Glues and TPD.
Novel Modality Development
Providing advanced technology for modalities requiring sophisticated deep learning, such as Molecular Glues and TPD.
Novel Modality Development
Providing advanced technology for modalities requiring sophisticated deep learning, such as Molecular Glues and TPD.
Targeted Therapeutics
Developing personalized treatments for cancer and intractable diseases by discovering candidates that selectively act on specific mutations.
Targeted Therapeutics
Developing personalized treatments for cancer and intractable diseases by discovering candidates that selectively act on specific mutations.
Targeted Therapeutics
Developing personalized treatments for cancer and intractable diseases by discovering candidates that selectively act on specific mutations.
Challenging Target Proteins
Discovering candidates for complex or undefined protein structures rapidly.
Challenging Target Proteins
Discovering candidates for complex or undefined protein structures rapidly.
Challenging Target Proteins
Discovering candidates for complex or undefined protein structures rapidly.

Experience the new standard of drug discovery
with DEEPMATCHER®
Get in Touch - DEEPMATCHER®
Get in Touch - DEEPMATCHER®
Get in Touch - DEEPMATCHER®
Get in Touch - DEEPMATCHER®
Get in Touch - DEEPMATCHER®
Get in Touch - DEEPMATCHER®
Explore LM-VS™
Explore LM-VS™
Explore LM-VS™
Explore LM-VS™
Explore LM-VS™
Explore LM-VS™

Global Premier AI
Drug Partner
Innovate with us.
Contact Us
Contact Us
© Syntekabio Co., Ltd. All rights reserved.
General Inquiries
Investor Relations / Press
Business Development / Partnerships
Data Center
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Global Premier AI
Drug Partner
Innovate with us.
Contact Us
Contact Us
© Syntekabio Co., Ltd. All rights reserved.
General Inquiries
Investor Relations / Press
Business Development / Partnerships
Data Center
Family Sites
© Syntekabio Co., Ltd. All rights reserved.