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LM-VS

Language Model-based Virtual Screening

LM-VS™ is an innovative virtual screening platform that combines AI screening with a Designed Scaffold based on protein structure analysis, enabling the rapid and precise identification of promising candidates within a vast compound library.

Learn more LM-VS™

Learn more LM-VS™

Learn more LM-VS™

Learn more LM-VS™

Breaking the Repetition Barrier —
LM-VS™’s Shortcut to Discovery

In the early stages of drug discovery, researchers go through countless experiments to identify promising candidate compounds. This process consumes a great deal of time and resources.
LM-VS™ minimizes trial-and-error by narrowing down the compound pool through AI-based virtual screening and structure-based Designed Scaffold modeling, leading to faster, more cost-effective candidate selection.

Syntekabio’s Role

in the Drug Discovery Journey

LM-VS™ is a core platform for hit discovery in small molecule drug research, designed to rapidly and precisely identify promising candidates from vast compound libraries.
Subsequent stages can be seamlessly connected with DeepMatcher® and ALGO™ to accelerate and streamline the drug development journey.

The Power of AI & Structural Design —
Accelerating Drug Discovery

LM-VS™ drastically accelerates the discovery of new drug candidates by screening massive chemical compound libraries using AI prediction models trained on 3D protein structure data.
The platform evaluates molecular structures with an AI model, then applies structural knowledge through Designed Scaffold to generate new molecules optimized for the target.
By minimizing repetitive experiments and maximizing efficiency, LM-VS™ has successfully identified hits within just a few months — a process that traditionally would have taken several years.

Core Process of LM-VS™

LM-VS™ streamlines the early-stage drug discovery process with AI,
enabling fast and precise identification of potential drug candidates.

01

Target Protein Selection

Begin the process by entering the name of the target protein or its gene symbol.

01

Target Protein Selection

Begin the process by entering the name of the target protein or its gene symbol.

01

Target Protein Selection

Begin the process by entering the name of the target protein or its gene symbol.

02

Pocket Detection & Scaffold Design

AI automatically detects the binding site of the protein and suggests the optimal core structure (Designed Scaffold).

02

Pocket Detection & Scaffold Design

AI automatically detects the binding site of the protein and suggests the optimal core structure (Designed Scaffold).

02

Pocket Detection & Scaffold Design

AI automatically detects the binding site of the protein and suggests the optimal core structure (Designed Scaffold).

03

AI-Based Virtual Screening

A vast compound library is screened using AI to rapidly identify candidates with high binding potential.

03

AI-Based Virtual Screening

A vast compound library is screened using AI to rapidly identify candidates with high binding potential.

03

AI-Based Virtual Screening

A vast compound library is screened using AI to rapidly identify candidates with high binding potential.

04

Candidate Filtering & Precision Evaluation

Hit compounds are ranked and selected based on structural and activity indicators such as binding affinity and stability.

04

Candidate Filtering & Precision Evaluation

Hit compounds are ranked and selected based on structural and activity indicators such as binding affinity and stability.

04

Candidate Filtering & Precision Evaluation

Hit compounds are ranked and selected based on structural and activity indicators such as binding affinity and stability.

Why LM-VS™ Matters

Scientific and Rational Approach

AI-driven screening and design based on 3D structural analysis of target proteins and extensive data

Scientific and Rational Approach

AI-driven screening and design based on 3D structural analysis of target proteins and extensive data

Innovative Time Reduction

Shortens candidate discovery from several years to a few weeks or months, significantly accelerating research

Innovative Time Reduction

Shortens candidate discovery from several years to a few weeks or months, significantly accelerating research

Efficient Cost Saving

Minimizes unnecessary experiments, improving R&D resource efficiency

Efficient Cost Saving

Minimizes unnecessary experiments, improving R&D resource efficiency

High Prediction Accuracy

Enhances success probability through structural simulation and AI learning

High Prediction Accuracy

Enhances success probability through structural simulation and AI learning

Why LM-VS™ Matters

Scientific and Rational Approach

AI-driven screening and design based on 3D structural analysis of target proteins and extensive data

Innovative Time Reduction

Shortens candidate discovery from several years to a few weeks or months, significantly accelerating research

Efficient Cost Saving

Minimizes unnecessary experiments, improving R&D resource efficiency

High Prediction Accuracy

Enhances success probability through structural simulation and AI learning

Key Application Areas

LM-VS™ is being applied in a wide range of research and development contexts by pharma and biotech companies.
Below are examples of how the platform is helping reshape drug discovery across diverse use cases:

Novel targets

Enables the discovery of new compounds for difficult-to-treat or previously untreatable targets.

Novel targets

Enables the discovery of new compounds for difficult-to-treat or previously untreatable targets.

Novel targets

Enables the discovery of new compounds for difficult-to-treat or previously untreatable targets.

Drug Repositioning

Applies existing compound libraries in new indications to improve efficacy and increase chances of clinical success.

Drug Repositioning

Applies existing compound libraries in new indications to improve efficacy and increase chances of clinical success.

Drug Repositioning

Applies existing compound libraries in new indications to improve efficacy and increase chances of clinical success.

Research scope expansion

Accelerates the identification of new candidates for a wider range of diseases, enabling companies to expand pipelines with fewer resources.

Research scope expansion

Accelerates the identification of new candidates for a wider range of diseases, enabling companies to expand pipelines with fewer resources.

Research scope expansion

Accelerates the identification of new candidates for a wider range of diseases, enabling companies to expand pipelines with fewer resources.

COVID-19

During the early days of the pandemic, LM-VS™ was used for urgent discovery of treatment candidates.

COVID-19

During the early days of the pandemic, LM-VS™ was used for urgent discovery of treatment candidates.

COVID-19

During the early days of the pandemic, LM-VS™ was used for urgent discovery of treatment candidates.

Discover how LM-VS™
helps biotech innovators streamline
early discovery and make smarter, faster decisions.

Discover how LM-VS™
helps biotech innovators streamline
early discovery and make smarter, faster decisions.

Learn more LM-VS™

Learn more LM-VS™

Learn more LM-VS™

Learn more LM-VS™

Learn more LM-VS™

Learn more LM-VS™

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Global Premier AI

Drug Partner

Innovate with us.

Contact Us

Contact Us

© Syntekabio Co., Ltd. All rights reserved.

General Inquiries

Investor Relations / Press

Business Development / Partnerships

Family Sites

© Syntekabio Co., Ltd. All rights reserved.